Organometallic Compounds
Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 hydrochloride | 2446474-09-3 | 96.6% | 250 MG
Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a 3-unit PEG linker used in PROTAC technology.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a Pomalidomide-based cereblon ligand
- Includes a 3-unit PEG linker
- Used in PROTAC technology
- Appears as a light yellow to yellow solid
- Structure consistent by 1H NMR spectrum
- Structure consistent by LCMS
- Purity of 96.6% by LCMS
- For research use only
Medchemexpress LLC ABT-639 | 1235560-28-7 | 99.3% | 455.91 | 50 MG
ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. It is used for research purposes only and not sold to patients. It effectively reduces nociceptive and neuropathic pain in rats.
- Blocks recombinant human T-type (Cav3.2) Ca2+ channels in a voltage-dependent fashion.
- Attenuates low voltage-activated (LVA) currents in rat DRG neurons.
- Significantly less active at other Ca2+ channels (e.g., Cav1.2 and Cav2.2).
- High oral bioavailability (%f=73) in rodents.
- Low protein binding (88.9%) in rodents.
- Low brain:plasma ratio (0.05:1) in rodents.
- Produces dose-dependent antinociception in a rat model of knee joint pain.
- Increases tactile allodynia thresholds in multiple models of neuropathic pain.
- Does not significantly alter hemodynamic or psychomotor function at higher doses.
Medchemexpress LLC Acetic acid, 2-(2,4-dichlorophenoxy)-, isooctyl ester | 25168-26-7 | 97.2% | 100 MG
2,4-D isooctyl ester is a selective herbicide of the chlorophenoxy compound class. It features a higher boiling point, low volatility, and low drift, making it suitable for controlling broadleaf weeds in various environments such as crops, lawns, and forests. It is for research use only.
- Selective herbicide of chlorophenoxy compound class
- Higher boiling point
- Low volatility
- Low drift
- Controls broadleaf weeds in crops, lawns, and forests
Medchemexpress LLC Bis-PEG5-PFP ester | 1334177-78-4 | 100 MG
Bis-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Contains two different ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase; the other targets the protein.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
Medchemexpress LLC D-ribofuranose-13C5 | 97.0% | 25mg
D-Ribofuranose-13C5 (D-Ribose-13C5) is the 13C-labeled D-Ribofuranose (HY-113375) D-Ribofuranose (D-Ribose) is an endogenous metabolite present in Cerebrospinal Fluid that can be used for the research of Ribose 5 Phosphate Isomerase Deficiency and Medium Chain Acyl Co A Dehydrogenase Deficiency[1][2]
eMolecules 13292-87-0 | Borane dimethyl sulfide complex | Oakwood Chemical | MFCD00013189 | 75.960 | C2H9BS | 0.000 | B.CSC | 2kg | 698445838
Borane dimethyl sulfide complex | Oakwood Chemical | 13292-87-0 | MFCD00013189 | 75.960 | C2H9BS | 0.000 | B.CSC | 2kg | 698445838
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 100 G
Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Peg-based protac linker
- Used in the synthesis of protacs
- Can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports
Medchemexpress LLC THP-PEG3-OH | 60221-37-6 | 98.7% | 10 G
THP-PEG3-OH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are compounds that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker, with one ligand binding to an E3 ubiquitin ligase and the other to the target protein.
- PEG-based PROTAC linker
- Molecular formula: C11H22O5
- Molecular weight: 234.29
- Appearance: Liquid
- Color: Colorless to light yellow
- For research use only
- Target: PROTAC linkers
- Pathway: PROTAC
- Storage (pure form): -20°C for 3 years; 4°C for 2 years
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 TFA | 2414913-97-4 | 99.0% | 1 G
Pomalidomide-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 5 (TFA)) is a synthetic E3 ligase ligand-linker conjugate composed of a Pomalidomide-based cereblon ligand and a 3-unit PEG linker. It can be utilized for the synthesis of PROTACs. This product is for research use only and not sold to patients.
- Molecular weight: 562.49
- Formula: C23H29F3N4O9
- Appearance: Solid-liquid mixture
- Color: Light yellow to yellow
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage: 4°C, stored under nitrogen, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture).
Medchemexpress LLC Phenyl 2-bromoacetate | 620-72-4 | 99.9% | 215.04 | 50 G
Phenyl 2-bromoacetate is a biochemical reagent suitable for life science related research. It is designed for laboratory use only and not for patient application. This compound exhibits an appearance that varies with temperature, being solid below 31°C and liquid above 33°C. It is typically colorless to off-white.
- High purity for reliable research results
- Temperature-dependent appearance (solid below 31°C, liquid above 33°C)
- Colorless to off-white in appearance
- Specific storage conditions for pure form and in solvent
- Well-defined solubility in DMSO and in vivo protocols